Mgr. Vít Herynek, Ph.D.: Curriculum Vitae
Center for Advanced Preclinical Imaging (CAPI)
First Faculty of Medicine, Charles University
Salmovská 3, 120 00, Prague
Czech Republic
tel.: +420 224 965 993
e-mail: vit.herynek@lf1.cuni.cz
Education
1993 – 1996 PhD study at the First Faculty of Medicine, Charles University, Prague
Thesis entitled: Optimization and Application of MR Spectroscopy and Imaging Methods.
1985 – 1990 Study at the Faculty of Mathematics and Physics, Charles University in Prague -
Specialization in biophysics and chemical physics.
Thesis entitled: Study of the Secondary Structure of Polyaminoacids by NMR Spectra.
International fellowship
1997 – 1999 visiting fellowship at National Institutes of Health – National Institute of Neurological Diseases and Stroke, Neuroimaging Branch, Bethesda, Maryland, USA
Work experience
2018 - Center for Advanced Preclinical Imaging (CAPI), First Faculty of Medicine, Charles University, Prague
1999 – 2018 Institute for Clinical and Experimental Medicine, Department of Radiodiagnostic and Interventional Radiology, MR Unit, Prague
2000 – 2010 Center for Cell Therapy and Tissue Repair
1996 – 1997 Institute for Experimental Medicine
1992 – 1993 Biophysical Institute of the First Faculty of Medicine, Charles University, Prague
Awards: Young Investigator’s Award, ESMRMB, Paris, 2000
Award of the Czech Neuropsychopharmacological Society, 2006
Membership: International Society for Magnetic Resonance in Medicine
European Society for Molecular Imaging
Investigator or co-investigator of a row of domestic and international projects
Author or co-author of more than 100 papers in journals with IF
Author of many educational and scientific lectures
H-index 24
Originator of patents
No. CZ301005 (2008) Process for preparing hybrid nanoparticles from nanoparticle agglomerates of complex multicomponent metal oxides
No. CZ307623 (2012) Water suspensions of cobalt-zinc ferrite nanoparticles as contrast agents for magnetic resonance imaging
No. CZ308154 (2019) Nanoparticles for magnetic and fluorescent cell labeling, preparation and utilization
Specialization during last five years (as is documented in recent papers):
· In vitro/in vivo molecular imaging using various imaging methods including bioluminescence, fluorescence, MR imaging, ultrasound and photoacoustic imaging
· Cell labeling and cell transplantation
· Novel contrast agent/cellular label development and testing
Five most recent papers
Nahorniak M,
Patsula V, Mareková D, Matouš P, Shapoval O, Oleksa V, Vosmanská M, Machová
Urdzíková L, Jendelová P, Herynek V, Horák D. Chemical and Colloidal Stability
of Polymer-Coated NaYF4:Yb,Er Nanoparticles in Aqueous Media and
Viability of Cells: The Effect of a Protective Coating. International
Journal of Molecular Sciences. 2023; 24(3):2724. https://doi.org/10.3390/ijms24032724
Ibrahim I,
Škoch A, Herynek V, Humhej I, Beran J, Flusserová V, Rolencová E, Juhaňáková M,
Brzák M, Nagy M, Tintěra J. Magnetic resonance tractography of the brachial
plexus: step-by-step. Quant Imaging Med Surg 2022;12(9):4488-45. DOI: https://dx.doi.org/10.21037/qims-22-30 Bui DT, Havelek
R, Královec K, Kubíčková L, Kuličková J, Matouš P, Herynek V, Kupčík J, Muthná D,
Řezanka P, Kaman O. Multimodal Contrast Agent Enabling pH Sensing Based on Organically
Functionalized Gold Nanoshells with Mn-Zn Ferrite Cores. Nanomaterials
2022, 12, 428. https://doi.org/10.3390/nano12030428 Neubertova V,
Guselnikova O, Yamauchi Y, Olshtrem A, Rimpelova S, Čižmár E, Orendáč M, Duchon
J, Volfova L, Lancok J, Herynek V, Fitl P, Ulbrich P, Jelinek L, Schneider P,
Kosek J, Postnikov P, Kolska Z, Svorcik V, Chertopalov S, Lyutakov O. Covalent
functionalization of Ti3C2T MXene flakes with Gd-DTPA
Complex for Stable and Biocompatible MRI Contrast Agent. Chem Eng J 2022,
446(2):136939. DOI: https://doi.org/10.1016/j.cej.2022.136939 Kolouchova K,
Cernochova Z, Groborz O, Herynek V, Koucky F, Jaksa R, Benes J, Slouf M, Hruby
M. Multiresponsive fluorinated polymers as a theranostic platform using 19F MRI.
European Polymer Journal 2022, 175:111381. DOI: https://doi.org/10.1016/j.eurpolymj.2022.111381
Bulte, J.W.M., Zhang, S.C., Van Gelderen, P., Herynek, V., Jordan, E.K., Duncan, I.D., Frank, J.A. Neurotransplantation of magnetically labeled oligodendrocyte progenitors: Magnetic resonance tracking of cell migration and myelination. Proceedings of the National Academy of Sciences of the United States of America. 1999, 96(26), 15256-15261. Cited 449×, IF=10,260
Babič, M., Horák, D., Trchová, M., Jendelová, P., Glogarová, K., Lesný, P., Herynek, V., Hájek, M., Syková, E. Poly (L-lysine)-modified iron oxide nanoparticles for stem cell labeling. Bioconjugate chemistry. 2008, 19(3), 740-750. Cited 263×, IF=4,584
Jendelová, P., Herynek, V., Urdziková, L., Glogarová, K., Kroupová, J., Andersson, B., Bryja, V., Burian, M., Hájek, M., Syková, E. Magnetic resonance tracking of transplanted bone marrow and embryonic stem cells labeled by iron oxide nanoparticles in rat brain and spinal cord. Journal of neuroscience research. 2004, 76(2), 232-243. Cited 247×, IF=3,727
Bryant, L.H., Brechbiel, M.W., Wu, C.C., Bulte, J.W.M., Herynek, V., Frank, J.A. Synthesis and relaxometry of high-generation (G = 5, 7, 9, and 10) PAMAM dendrimer-DOTA-gadolinium chelates. Journal of magnetic resonance imaging. 1999, 9(2), 348-352. Cited 209×, IF=3,001
Jendelová, P., Herynek, V., De Croos, J., Glogarová, K., Andersson, B., Hájek, M., Syková, E. Imaging the fate of implanted bone marrow stromal cells labeled with superparamagnetic nanoparticles. Magnetic resonance in medicine. 2003, 50(4), 767-776. Cited 179×, IF=3,313