1. lékařská fakulta Univerzita Karlova 1. lékařská fakulta Univerzita Karlova
vherynek 19.01.2022

Publikace CAPI

 

2021


Honěk J, Šrámek M, Honěk T, Tomek A, Šefc L, Januška J, Fiedler J, Horváth M, Novotný Š, Brabec M, Veselka J. Screening and Risk Stratification Strategy Reduced Decompression Sickness Occurrence in Divers With Patent Foramen Ovale. JACC Cardiovasc Imaging. 2021 Aug 12: S1936-878X(21)00509-X. doi: 10.1016/j.jcmg.2021.06.019

Báječný M, Chen CL, Faltusová K, Heizer T, Szikszai K, Páral P, Šefc L, Nečas E. Hematopoiesis Remains Permissive to Bone Marrow Transplantation After Expansion of Progenitors and Resumption of Blood Cell Production. Front Cell Dev Biol. 2021 Aug 3; 9:660617. doi: 10.3389/fcell.2021.660617

Albuquerque LJC, Sincari V, Jäger A, Kucka J, Humajova J, Pankrac J, Paral P, Heizer T, Janouškova O, Davidovich I, Talmon Y, Pouckova P, Štěpánek P, Sefc L, Hruby M, Giacomelli FC, Jäger E. pH-responsive polymersome-mediated delivery of doxorubicin into tumor sites enhances the therapeutic efficacy and reduces cardiotoxic effects. J Control Release. 2021 Apr 10; 332:529-538. doi: 10.1016/j.jconrel.2021.03.013

Jäger E, Humajová J, Dölen Y, Kučka J, Jäger A, Konefał R, Pankrác J, Pavlova E, Heizer T, Šefc L, Hrubý M, Figdor CG, Verdoes M. Enhanced Antitumor Efficacy through an "AND gate" Reactive Oxygen-Species-Dependent pH-Responsive Nanomedicine Approach. Adv Healthcare Mater. 2021 Jul;10(13):e2100304. doi: 10.1002/adhm.202100304

Loukotova L, Svec P, Groborz O, Heizer T, Benes H, Raabova H, Belinova T, Herynek V, Hruby M. Direct Comparison of Analogous Amphiphilic Gradient and Block Polyoxazolines. Macromolecules. 2021; 54(17):8182-8194. DOI: 10.1021/acs.macromol.0c02674

 Keša P, Paúrová M, Babič M, Heizer T, Matouš P, Turnovcová K, Mareková D, Šefc L, Herynek V. Photoacoustic Properties of Polypyrrole Nanoparticles. Nanomaterials. 2021; 11(9):2457. https://doi.org/10.3390/nano11092457

Kolokithas-Ntoukas A, Bakandritsos A, Belza J, Kesa P, Herynek V, Pankrac J, Angelopoulou A, Malina O, Avgoustakis K, Georgakilas V, Polakova K, Zboril R. Condensed Clustered Iron Oxides for Ultrahigh Photothermal Conversion and In Vivo Multimodal Imaging. ACS Appl Mater Interfaces. 2021; 13(25):29247-29256, doi: 10.1021/acsami.1c00908

Paúrová M, Taboubia O, Šeděnková I, Hromádková J, Matouš P, Herynek V, Šefc L, Babič M. Role of dextran in stabilization of polypyrrole nanoparticles for photoacoustic imaging. European Polymer Journal. 2021; 110634, https://doi.org/10.1016/j.eurpolymj.2021.110634

 Kubíčková L, Kaman O, Veverka P, Herynek V, Brázda P, Bernášek K, Veverka M, Kohout J. Magnetic properties, 57Fe Mössbauer spectroscopy and 1H NMR relaxometry of ε-Fe2−xGaxO3 nanoparticles: The effect of gallium doping on magnetic and MRI performance. Journal of Alloys and Compounds. 2021; 856:158187. https://doi.org/10.1016/j.jallcom.2020.158187  

Turnovcova K, Marekova D, Sursal T, Krupova M, Gandhi R, Krupa P, Kaiser R, Herynek V, Netuka D, Jendelova P, Jhanwar-Uniyal M. Understanding the Biological Basis of Glioblastoma Patient-derived Spheroids. Anticancer Research. 2021; 41:1183-1195.  https://doi.org/10.21873/anticanres.14875

Veverka P, Kubíčková L, Jirák Z, Herynek V, Veverka M, Kaman O. Temperature and field dependences of transverse relaxivity of Co-Zn ferrite nanoparticles coated with silica: the role of magnetic properties and different regimes. Materials Chemistry and Physics. 2021; 260:124178. DOI: https://doi.org/10.1016/j.matchemphys.2020.124178

Shapoval O, Oleksa V, Šlouf M, Lobaz V, Trhlíková O, Filipová M, Janoušková O, Engstová H, Pankrác J, Modrý A, Herynek V, Ježek P, Šefc L, Horák D. Colloidally Stable P(DMA-AGME)-Ale-Coated Gd(Tb)F3:Tb3+(Gd3+),Yb3+,Nd3+ Nanoparticles as a Multimodal Contrast Agent for Down- and Upconversion Luminescence, Magnetic Resonance Imaging, and Computed Tomography. Nanomaterials. 2021; 11(1):230. https://doi.org/10.3390/nano11010230

Herynek V, Babič M, Kaman O, Charvátová H, Veselá M, Buchholz O, Vosmanská M, Kubániová D, Kohout J, Hofmann UG, Šefc L. Maghemite nanoparticles coated by methacrylamide-based polymer for magnetic particle imaging. J Nano Res. 2021; 23:52. DOI: 10.1007/s11051-021-05164-x

Ibrahim I, Škoch A, Herynek V, Jírů F, Tintěra J. Magnetic resonance tractography of the lumbosacral plexus. Step-by-step. Medicine. Feb 12, 2021; 100(6):e24646. DOI: 10.1097/MD.0000000000024646

Pola R, Pokorná E, Vočková P, Böhmová E, Pechar M, Karolová J, Pankrác J, Šefc L, Helman K, Trněný M, Etrych T, Klener P. Cytarabine nanotherapeutics with increased stability and enhanced lymphoma uptake for tailored highly effective therapy of mantle cell lymphoma. Acta Biomaterialia. 2021; 119: 349-359. https://doi.org/10.1016/j.actbio.2020.11.014.


Oleshchuk D, Šálek P, Dvořáková J, Kučka J, Pavlova E, Francová P, Šefc L, Prokš V. Biocompatible polypeptide nanogel: Effect of surfactants on nanogelation in inverse miniemulsion, in vivo biodistribution and blood clearance evaluation. Mater Sci Eng C. 2021; 126:111865. https://doi.org/10.1016/j.msec.2021.111865

Keša P, Pokorná E, Grajciarová M, Tonar Z, Vočková P, Trochet P, Kopeček M, Jakša R, Šefc L, Klener P. Quantitative In Vivo Monitoring of Hypoxia and Vascularization of Patient-Derived Murine Xenografts of Mantle Cell Lymphoma Using Photoacoustic and Ultrasound Imaging. Ultrasound in Medicine & Biology. 2021; 47(4):1099-1107. https://doi.org/10.1016/j.ultrasmedbio.2020.12.010

Moskvin M, Huntošová V, Herynek V, Matouš P, Michalcová A, Lobaz V, Zasońska B, Šlouf M, Seliga R, Horák D. In vitro cellular activity of maghemite/cerium oxide magnetic nanoparticles with antioxidant properties. Colloids and Surfaces B: Biointerfaces. 2021; 204:111824. https://doi.org/10.1016/j.colsurfb.2021.111824


2020


Wong WS, Alozy J, Ballabriga R, Campbell M, Kremastiotis I, Llopart X, Poikela T, Sriskaran V, Tlustos L, Turecek D. Introducing Timepix2, a frame-based pixel detector readout ASIC measuring energy deposition and arrival time. Radiation Measurements. 2020; 131:106230. DOI: 10.1016/j.radmeas.2019.106230 .

Dreier ES, Silvestre C, Kehres J, Turecek D, Khalil M, Hemmingsen JH, Hansen O, Jakubek J, Feidenhans’l R, and Olsen UL. Single-shot, omni-directional x-ray scattering imaging with a laboratory source and single-photon localization. Optics Letters. 2020; 45(4):1021-1024. DOI: 10.1364/OL.381420

Herynek V, Babič M, Kaman O, Charvátová H, Veselá M, Šefc L. Development of novel nanoparticles for MPI. International Journal on Magnetic Particle Imaging. 2020; 6(2), Suppl 1, Article ID 2009019. https://doi.org/10.18416/IJMPI.2020.2009019

 

Kozler P, Herynek V, Marešová D, Perez PD, Šefc L, Pokorný J. Effect of Methylprednisolone on Experimental Brain Edema in Magnetic Resonance Imaging. Physiol Res. 2020; 69: 919-926. https://doi.org/10.33549/physiolres.934460


Dezortova M, Lescinskij A, Dušek P, Herynek V, Acosta-Cabronero J, Bruha R, Jiru F, Robinson SD, Hajek M. Multiparametric quantitative brain MRI in neurological and hepatic forms of Wilson’s disease. J Magn Reson Imaging. 2020; 108(8): 1563-1578. DOI: 10.1002/jmri.26984

Groborz O, Poláková L, Kolouchová K, Švec P, Loukotová L, Miriyala VM, Francová P, Kučka J, Krijt J, Páral P, Báječný M, Heizer T, Pohl R, Dunlop D, Czernek J, Šefc L, Beneš J, Štěpánek P, Hobza P, Hrubý M. Chelating Polymers for Hereditary Hemochromatosis Treatment. Macromol Biosci. 2020 Sep 21: e2000254. doi: 10.1002/mabi.202000254 .

Honěk J, Šrámek M, Honěk T, Tomek A, Šefc L, Januška J, Fiedler J, Horváth M, Novotný Š, Veselka J. Patent Foramen Ovale Closure Is Effective in Divers: Long-Term Results From the DIVE-PFO Registry. J Am Coll Cardiol. 2020; 76(9):1149-1150. doi: 10.1016/j.jacc.2020.06.072 .

Kubíčková L, Kaman L, Veverka P, Herynek V, Brázda P, Vosmanská M, Kmječ T, Dvořák P, Kubániová D, Kohout J. The epsilon-AlxFe2-xO3 nanomagnets as MRI contrast agents: Factors influencing transverse relaxivity. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 2020; 589(2):204–214. doi: 10.1016/j.colsurfa.2020.124423.


Královec K, Havelek R, Koutová D, Veverka P, Kubíčková L, Brázda P, Kohout J, Herynek V, Vosmanská M, Kaman O. Magnetic nanoparticles of Ga-substituted ε-Fe2O3 for biomedical applications: magnetic properties, transverse relaxivity and effects of silica-coated particles on cytoskeletal networks. J Biomed Mater Res A. 2020 108(7):1563-1578.  DOI: 10.1002/jbm.a.36926

Kostiv, U, Kucka, J, Lobaz, V, Kotov, N, Janouskova, O, Slouf, M, Krajnik, B, Podhorodecki, A, Francova, P, Sefc, L, Jirak, D, Horak, D. Highly colloidally stable trimodal I-125-radiolabeled PEG-neridronate-coated upconversion/magnetic bioimaging nanoprobes. SCIENTIFIC REPORTS. 2020;10(1):20016. DOI: 10.1038/s41598-020-77112-z 


Jager E., Sincari V., Albuquerque LJC, Jager A., Humajova J., Kucka J., Pankrac J., Paral P., Heizer T., Konefal R., Pavlova E., Sedlacek O., Giacomelli FC, Pouckova P., Sefc L., Stepanek P., Hruby M. Reactive oxygen species (ROS)-responsive polymersomes with site-specific chemotherapeutic delivery into ROS-rich tumors in vivo. Biomacromolecules. 2020 Feb 21. DOI:10.1021/acs.biomac.9b01748,


Walter A., Paul-Gilloteaux P., Plochberger B., Sefc L., Verkade P., Mannheim JG, Slezak P., Unterhuber A., Marchetti-Deschmann M., Ogris M., Bühler K., Fixler D., Geyer S., Weninger W., Glösmann M., Handschuh S. and Wanek T. Correlated Multimodal Imaging in Life Sciences: Expanding the Biomedical Horizon. Front Phys. 8:47. 2020, DOI:10.3389/fphy.2020.00047



R Pola, E Böhmová, M Filipová, M Pechar, J Pankrác, D Větvička, T Olejár, M Kabešová, P Poučková, L Šefc, M Zábrodský, O Janoušková, J Bouček, and T Etrych. Targeted Polymer-Based Probes for Fluorescence Guided Visualization and Potential Surgery of EGFR-Positive Head-and-Neck Tumors. Pharmaceutics 2020, 12(1), 31; DOI: 10.3390/pharmaceutics12010031


Turecek D, Jakubek J, Trojanova E, Sefc L. Single layer Compton camera based on Timepix3 technology. Journal of Instrumentation. 2020;15(01):C01014-C. DOI: 10.1088/1748-0221/15/01/c01014




2019




Dreier, E. S., Silvestre, C.,  Kehres, J. , Tureček, D., Khalil, M.,  Hemmingsen, J. H., Hansen, O., Jakubek, J. - Feidenhans'l, R.,  Olsen, U. L.. Virtual subpixel approach for single-mask phase-contrast imaging using Timepix3. Journal of Instrumentation. 2019, 14(January), C01011. ISSN 1748-0221. DOI: 10.1088/1748-0221/14/01/C01011

Felix-Bautista, R., Gehrke, T., Ghesquiere-Dierickx, L., Reimold, M., Amato, C. - Tureček, D., Jakubek, J., Ellerbrock, M., Martisikova, M.. Experimental verification of a non-invasive method to monitor the lateral pencil beam position in an anthropomorphic phantom for carbon-ion radiotherapy. Physics in Medicine and Biology. 2019, 64(17), 175019. ISSN 0031-9155. DOI: 10.1088/1361-6560/ab2ca3

Gálisová, A, Herynek, V., Swider, E., Sticová, E., Pátíková, A., Kosinová, L., Kříž, J.,  Hájek, M. ,Srinivas, M., Jirák, D. A Trimodal Imaging Platform for Tracking Viable Transplanted Pancreatic Islets In Vivo: F-19 MR, Fluorescence, and Bioluminescence Imaging. Molecular Imaging and Biology. 2019, 21(3), 454-464. ISSN 1536-1632. DOI: 10.1007/s11307-018-1270-3

Herynek, V., Turnovcová, K., Galisova, A., Kaman, O., Marekova, D., Koktan, J. Vosmanska, M., Kosinova, L., Jendelova, P. Manganese-Zinc Ferrites: Safe and Efficient Nanolabels for Cell Imaging and Tracking In Vivo. ChemistryOpen [online]. 2019, 8(2), 155-165. ISSN 2191-1363. DOI: 10.1002/open.201800261


Herynek, V., Martinisková, M., Bobrova, Y., -Gálisová, A., Kotek, J., Hermann, P., Koucký, F., Jirák, D., Hájek, M. Low-molecular-weight paramagnetic F-19 contrast agents for fluorine magnetic resonance imaging. Magnetic Resonance Materials in Physics, Biology, and Medicine. 2019, 32(1), 115-122. ISSN 0968-5243. DOI: 10.1007/s10334-018-0721-9


Honěk, J., Šrámek, M.,Šefc, L., Januška, J., Fiedler, J., Horvárh, M., Tomek, A., Novotný, Š.,  Honěk, T., Veselka, J. High-grade patent foramen ovale is a risk factor of unprovoked decompression sickness in recreational divers. Journal of Cardiology. 2019, 74(6), 519-523. ISSN 0914-5087. DOI: 10.1016/j.jjcc.2019.04.014

Hromádková, V., Francová, P., Báječný, M., Jonáš, F., Molitor, M., Šefc, L., Měšťák, O. The CD34 Cell Number Alone Predicts Retention of the Human Fat-Graft Volume in a Nude Mouse Model. Folia Biologica. 2019, 65(2), 64-69. ISSN 0015-5500


Khalil, M., Tureček, D., Jakubek, J., Kehres, J., Dreier, E. S., Olsen, U. L. Intrinsic XRF corrections in Timepix3 CdTe spectral detectors. Journal of Instrumentation. 2019, 14(January), C01018. ISSN 1748-0221. DOI: 10.1088/1748-0221/14/01/C01018


Kubíčková, L., Brázda, P., Veverka, M., Kaman, O., Herynek, V.,Vosmanská, M., Dvořák, P., - Bernášek, K.,  Kohout, J. Nanomagnets for ultra-high field MRI: Magnetic properties and transverse relaxivity of silica-coated ε-Fe2O3. Journal of Magnetism and Magnetic Materials. 2019, 480(February 2019), 154-163. ISSN 0304-8853. DOI: 10.1016/j.jmmm.2019.02.067


Malina, T., Poláková,K., Skopalík, J., Milotová, V.,Holá, K., Havrdová, M., Bartoň Tománková, K - Čmiel, V., Šefc, L., Zbořil, R. Carbon dots for in vivo fluorescence imaging of adipose tissue-derived mesenchymal stromal cells. Carbon. 2019, 152(November), 434-443. ISSN 0008-6223. DOI:10.1016/j.carbon.2019.05.061




Patsula, V., Horák, D., Kučka, J., Macková, H., Lobaz, V., Francová, P., Herynek, V., Heizer, T., Páral, P., Šefc, L. Synthesis and modification of uniform PEG-neridronate-modified magnetic nanoparticles determines prolonged blood circulation and biodistribution in a mouse preclinical model. Scientific Reports. 2019, 9(July), 10765. ISSN 2045-2322. DOI: 10.1038/s41598-019-47262-w


Pola, R., Parnica, J., Zuska, K., Bohmová, E.,  Filipová, M., Pechar, M., Pankrác, J.,Mucksová, J., Kalina, J., Trefil, P., Šefc, L.,Větvička, D., Poučková, P., Bouček, J., Janoušková, O., Etrych, T. Oligopeptide-targeted polymer nanoprobes for fluorescence-guided endoscopic surgery. Multifunctional Materials. 2019, 2(2). ISSN 2399-7532. DOI: 10.1088/2399-7532/ab159e


                                                                                                            

2018




Páral P, Faltusová K, Molík M, Renešová N, Šefc L, Nečas E. Cell cycle and differentiation of Sca-1+ and Sca-1- hematopoietic stem and progenitor cells. Cell Cycle. 2018;17(16):1979-1991. DOI:  10.1080/15384101.2018.1502573. Epub 2018 Sep 11


Kaman O, Herynek V, Veverka P, Kubickova L, Pashchenko M, Kulickova J, Jirak Z. Transverse Relaxivity of Nanoparticle Contrast Agents for MRI: Different Magnetic Cores and Coatings. IEEE TRANSACTIONS ON MAGNETICS. Volume: 54 Issue: 11 Article Number: 5300405, DOI: 10.1109/TMAG.2018.2844253, NOV 2018


Khalil M., Turecek D., Jakubek J., Kehres J., Dreier E.S., Olsen U.L., Intrinsic XRF correction in Timepix3 CdTe spectral detectors, JINST Vol 14, C01018 (2019), DOI: 10.1088/1748-0221/14/01/C01018


Dreier E.S., Silvestre C., Kehres J., Turecek D., Khalil M., Hemmingsen J.H., Hansen O., Jakubek J., Feidenhands I., Olsen U.L, Virtual subpixel approach for single-mask phase-contrast imaging using Timepix3., JINST Vol 14, C01011 (2019), DOI: 10.1088/1748-0221/14/01/C01011


Turecek D., Jakubek J., Trojanova E., Sefc L., Compton camera based on Timepix3 technology. JINST Vol 13, C11022 (2018) DOI: 10.1088/1748-0221/13/11/C11022


Turecek, Daniel; Jakubek, Jan; Trojanova, Eliska; Sefc, Ludek; Kolarova, Vera. Application of Timepix3 based CdTe spectral sensitive photon counting detector for PET imaging. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT Volume: 895 Pages: 84-89 Published: JUL 1 2018


Etrych T, Daumová L, Pokorná E, Tušková D, Lidický O, Kolářová V, Pankrác J, Šefc L, Chytil P, Klener P. Effective doxorubicin-based nano-therapeutics for simultaneous malignant lymphoma treatment and lymphoma growth imaging. J Control Release. 2018 Sep 22;289:44-55. DOI: 10.1016/j.jconrel.2018.09.018


Herynek V, Martinisková M, Bobrova Y, Gálisová A, Kotek J, Hermann P, Koucký F, Jirák D, Hájek M. Low-molecular-weight paramagnetic 19F contrast agents for fluorine magnetic resonance imaging. MAGMA. 2018 Nov 29. DOI: 10.1007/s10334-018-0721-9


Vetrik M, Mattova J, Mackova H, Kucka J, Pouckova P, Kukackova O, Brus J, Eigner-Henke S, Sedlacek O, Sefc L, Stepanek P, Hruby M. Biopolymer strategy for the treatment of Wilson's disease- J Control Release. 2018 Mar 10;273:131-138. DOI: 10.1016/j.jconrel.2018.01.026. Epub 2018 Feb 2


Trojanova,E. Jakubek, J. Turecek, D. Sykora, V. Francova, P. Kolarova V. and Sefc, L. Evaluation of Timepix3 based CdTe photon counting detector for fully spectroscopic small animal SPECT imaging. Journal of Instrumentation, 13(01):C01001-C01001. DOI: 10.1088/1748-0221/13/01/C01001. January 2018



2017

 


Gehrke, T., Burigo, L., Arico, G., Berke, S., Jakubek, J., Tureček, D., Tessonnier, T., Mairani, A.,  Martisikova, M. Energy deposition measurements of single H-1, He-4 and C-12 ions of therapeutic energies in a silicon pixel detector. Journal of Instrumentation. 2017, 12(April), P04025. ISSN 1748-0221. DOI: 10.1088/1748-0221/12/04/P04025

Kostiv, U., Lobaz, V., Kučka, J., Švec, P., Sedláček, O.,Hrubý, M., Janoušková, O., Francová, P. Kolářová, V.,  Šefc, L., Horák, D. A simple neridronate-based surface coating strategy for upconversion nanoparticles: highly colloidally stable 125I-radiolabeled NaYF4:Yb3+/Er3+@PEG nanoparticles for multimodal in vivo tissue imaging. Nanoscale. 2017, 9(43), 16680-16688. ISSN 2040-3364. DOI:10.1039/c7nr05456d
Loukotová, L., Kučka, J., Rabyk, M., Hocherl, A., Venclíková, K., - Janoušková, O., Páral, P., Kolářová, V., Heizer, T., Šefc, L., Štěpánek, P., Hrubý, M. Thermoresponsive beta-glucan-based polymers for bimodal immunoradiotherapy - Are they able to promote the immune system?. Journal of Controlled Release. 2017, 268(December), 78-91. ISSN 0168-3659. DOI: 10.1016/j.jconrel.2017.10.010
Šefc, L. Recent Progress in MPI Imaging Methodology, Scanner Instrumentation, and Image Reconstruction. International Journal on Magnetic Particle Imaging. 2017, 3(1). ISSN 2365-9033. DOI: 10.18416/ijmpi.2017.1706000

Trojanová, E.,  Schyns, L. E. J. R., Ludwig, D.,  Jakubek, J., Le Pape, A., Šefc, L., Lotte, S. Sýkora, V., Tureček, D,. Uher, J. Verhaegen, F. Tissue sensitive imaging and tomography without contrast agents for small animals with Timepix based detectors. Journal of Instrumentation. 2017, 12(January), C01056. ISSN 1748-0221. DOI: 10.1088/1748-0221/12/01/C01056


2016

Tureček, D., Jakubek, J., Soukup, P. USB 3.0 readout and time-walk correction method for Timepix3 detector. Journal of Instrumentation. 2016, 11(December), C12065. ISSN 1748-0221. DOI: 10.1088/1748-0221/11/12/C12065



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