Publikace CAPI

• Nahorniak M, Pop-Georgievski O, Velychkivska N, Filipová M, Rydvalová E, Gunár K, Matouš P, Kostiv U, Horák D. Rose Bengal-Modified Upconverting Nanoparticles: Synthesis, Characterization, and Biological Evaluation. Life (Basel). 2022, 12(9):1383. https://doi.org/10.3390/life12091383

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• Ibrahim I, Škoch A, Herynek V, Humhej I, Beran J, Flusserová V, Rolencová E, Juhaňáková M, Brzák M, Nagy M, Tintěra J. Magnetic resonance tractography of the brachial plexus: step-by-step. Quant Imaging Med Surg. 2022; 12(9):4488-45. http://doi.org/ 10.21037/qims-22-30

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• Kolouchova K, Cernochova Z, Groborz O, Herynek V, Koucky F, Jaksa R, Benes J, Slouf M, Hruby M. Multiresponsive fluorinated polymers as a theranostic platform using 19F MRI. Eur. Polym. J. 2022, 175:111381. https://doi.org/10.1016/j.eurpolymj.2022.111381

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• Neubertova V, Guselnikova O, Yamauchi Y, Olshtrem A, Rimpelova S, Čižmár E, Orendáč M, Duchon J, Volfova L, Lancok J, Herynek V, Fitl P, Ulbrich P, Jelinek L, Schneider P, Kosek J, Postnikov P, Kolska Z, Svorcik V, Chertopalov S, Lyutakov O. Covalent functionalization of Ti3C2T MXene flakes with Gd-DTPA Complex for Stable and Biocompatible MRI Contrast Agent. Chem Eng J. 2022, 446(2):136939. https://doi.org/10.1016/j.cej.2022.136939

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• Bui DT, Havelek R, Královec K, Kubíčková L, Kuličková J, Matouš P, Herynek V, Kupčík J, Muthná D, Řezanka P, Kaman O. Multimodal Contrast Agent Enabling pH Sensing Based on Organically Functionalized Gold Nanoshells with Mn-Zn Ferrite Cores. Nanomaterials. 2022, 12(3):428. https://doi.org/10.3390/nano12030428

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  Groborz O, Kolouchová K, Pankrác J, Keša P, Kadlec J, Krunclová T, Pierzynová A, Šrámek J, Hovořáková M, Dalecká L, Pavlíková Z, Matouš P, Páral P, Loukotová L, Švec P, Beneš H, Štěpánek L, Dunlop D, Melo CV, Šefc L, Slanina T, Beneš J, Van Vlierberghe S, Hoogenboom R, Hrubý M. Pharmacokinetics of Intramuscularly Administered Thermoresponsive Polymers. Adv. Healthcare Mater. 2022, 11:2201344. https://doi.org/10.1002/adhm.202201344

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• Karalko A, Keša P, Jelínek F, Šefc L, Ježek J, Zemánek P, Grus T. In Vivo Contrast Imaging of Rat Heart with Carbon Dioxide Foam. Sensors. 2022; 22(14):5124. https://doi.org/10.3390/s22145124

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• Modrý A, Dammer J, Trojanová E, Jakubek J, Sýkora V, Šefc L. SPECT imaging properties of the CdTe-Timepix3 detector used in a new prototype FullSPECT 3D multimodal preclinical imaging system: Comparison with scintillation gamma camera. Nucl. Instrum. Methods Phys. Res. A: Accel. Spectrom. Detect. Assoc. Equip. 1032:166531. https://doi.org/10.1016/j.nima.2022.166531

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• Vetrik M, Kucka J, Kobera L, Konefal R, Lobaz V, Pavlova E, Bajecny M, Heizer T, Brus J, Sefc L, Pratx G, Hruby M. Fluorinated diselenide nanoparticles for radiosensitizing therapy of cancer. Free Radic. Biol. Med. 2022,187. https://doi,org/10.1016/j.freeradbiomed.2022.05.015

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• Honěk J, Šrámek M, Honěk T, Tomek A, Šefc L, Januška J, Fiedler J, Horváth M, Novotný Š, Brabec M, Veselka J. Screening and Risk Stratification Strategy Reduced Decompression Sickness Occurrence in Divers With Patent Foramen Ovale. JACC Cardiovasc Imaging. 2022 Feb;15(2):181-189. http://doi.org/10.1016/j.jcmg.2021.06.019

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• Kolouchova K, Groborz O, Slouf M, Herynek V, Parmentier L, Babuka D, Cernochova Z, Koucky F, Sedlacek O, Hruby M, Hoogenboom R, Van Vlierberghe S. Thermoresponsive Triblock Copolymers as Widely Applicable 19F Magnetic Resonance Imaging Tracers. Chem. Mater. 2022;34(24):10902-10916. https://doi.org/10.1021/acs.chemmater.2c02589

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• Sramek M, Honek J, Tomek A, Ruzickova T, Honek T, Sefc L. Risk stratification of neurological decompression sickness in divers. Bratisl Med J. 2022;123(2):77-82. https://doi.org/10.4149/BLL_2022_022 

2021

• Palma Alejandro K., Sefc L. Single photon emission computed tomography. In book: Imaging Modalities for Biological and Preclinical Research: A Compendium, Volume 2, II.11-1, Eds. Walter A, Mannheim JG, and Caruana CJ. IOP Publishing Ltd 2021. https://doi.org/10.1088/978-0-7503-3747-2ch15

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• Pola R, Pokorná E, Vočková P, Böhmová E, Pechar M, Karolová J, Pankrác J, Šefc L, Helman K, Trněný M, Etrych T, Klener P. Cytarabine nanotherapeutics with increased stability and enhanced lymphoma uptake for tailored highly effective therapy of mantle cell lymphoma. Acta Biomater. 2021;119:349-359. https://doi.org/10.1016/j.actbio.2020.11.014

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• Jäger E, Humajová J, Dölen Y, Kučka J, Jäger A, Konefał R, Pankrác J, Pavlova E, Heizer T, Šefc L, Hrubý M, Figdor CG, Verdoes M. Enhanced Antitumor Efficacy through an "AND gate" Reactive Oxygen-Species-Dependent pH-Responsive Nanomedicine Approach. Adv Health Mater. 2021;10(13):e2100304. https://doi.org/10.1002/adhm.202100304

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• Albuquerque LJC, Sincari V, Jäger A, Kucka J, Humajova J, Pankrac J, Paral P, Heizer T, Janouškova O, Davidovich I, Talmon Y, Pouckova P, Štěpánek P, Sefc L, Hruby M, Giacomelli FC, Jäger E. pH-responsive polymersome-mediated delivery of doxorubicin into tumor sites enhances the therapeutic efficacy and reduces cardiotoxic effects. J Control Release. 2021;332:529-538. https://doi.org/10.1016/j.jconrel.2021.03.013

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• Báječný M, Chen CL, Faltusová K, Heizer T, Szikszai K, Páral P, Šefc L, Nečas E. Hematopoiesis Remains Permissive to Bone Marrow Transplantation After Expansion of Progenitors and Resumption of Blood Cell Production. Front Cell Dev Biol. 2021;9:660617. https://doi.org/10.3389/fcell.2021.660617

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• Moskvin M, Huntošová V, Herynek V, Matouš P, Michalcová A, Lobaz V, Zasońska B, Šlouf M, Seliga R, Horák D. In vitro cellular activity of maghemite/cerium oxide magnetic nanoparticles with antioxidant properties. Colloids Surf. B: Biointerfaces. 2021,204:111824. https://doi.org/10.1016/j.colsurfb.2021.111824

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• Keša P, Pokorná E, Grajciarová M, Tonar Z, Vočková P, Trochet P, Kopeček M, Jakša R, Šefc L, Klener P. Quantitative In Vivo Monitoring of Hypoxia and Vascularization of Patient-Derived Murine Xenografts of Mantle Cell Lymphoma Using Photoacoustic and Ultrasound Imaging. Ultrasound Med. Biol. 2021;47(4):1099-1107. https://doi.org/10.1016/j.ultrasmedbio.2020.12.010

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• Oleshchuk D, Šálek P, Dvořáková J, Kučka J, Pavlova E, Francová P, Šefc L, Proks V. Biocompatible polypeptide nanogel: Effect of surfactants on nanogelation in inverse miniemulsion, in vivo biodistribution and blood clearance evaluation. Mater. Sci. Eng. C-Mater. Biol. Appl. 2021;126:111865. https://doi.org/10.1016/j.msec.2021.111865

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• Ibrahim I, Škoch A, Herynek V, Jírů F, Tintěra J. Magnetic resonance tractography of the lumbosacral plexus. Step-by-step. Medicine. 2021,100(6):e24646. https://doi.org/10.1097/MD.0000000000024646

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• Herynek V, Babič M, Kaman O, Charvátová H, Veselá M, Buchholz O, Vosmanská M, Kubániová D, Kohout J, Hofmann UG, Šefc L. Maghemite nanoparticles coated by methacrylamide-based polymer for magnetic particle imaging. J. Nanopart. Res. 2021,23:52. htps://doi.org/10.1007/s11051-021-05164-x

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• Shapoval O, Oleksa V, Šlouf M, Lobaz V, Trhlíková O, Filipová M, Janoušková O, Engstová H, Pankrác J, Modrý A, Herynek V, Ježek P, Šefc L, Horák D. Colloidally Stable P(DMA-AGME)-Ale-Coated Gd(Tb)F3:Tb3+(Gd3+),Yb3+,Nd3+ Nanoparticles as a Multimodal Contrast Agent for Down- and Upconversion Luminescence, Magnetic Resonance Imaging, and Computed Tomography. Nanomaterials (Basel). 2021;11(1):230. https://doi.org/10.3390/nano11010230

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• Veverka P, Kubíčková L, Jirák Z, Herynek V, Veverka M, Kaman O. Temperature and field dependences of transverse relaxivity of Co-Zn ferrite nanoparticles coated with silica: the role of magnetic properties and different regimes. Mater. Chem. Phys. 2021, 260:124178. https://doi.org/10.1016/j.matchemphys.2020.124178

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• Turnovcova K, Marekova D, Sursal T, Krupova M, Gandhi R, Krupa P, Kaiser R, Herynek V, Netuka D, Jendelova P, Jhanwar-Uniyal M. Understanding the Biological Basis of Glioblastoma Patient-derived Spheroids. Anticancer Res. 2021; 41:1183-1195. https://doi.org/10.21873/anticanres.14875

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• Kubíčková L, Kaman O, Veverka P, Herynek V, Brázda P, Bernášek K, Veverka M, Kohout J. Magnetic properties, 57Fe Mössbauer spectroscopy and 1H NMR relaxometry of ε-Fe2−xGaxO3 nanoparticles: The effect of gallium doping on magnetic and MRI performance. J. Alloys Compd. 2021; 856:158187. https://doi.org/10.1016/j.jallcom.2020.158187

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• Paurova M, Taboubi O, Sedenkova I, Hromadkova J, Matous P, Herynek V, Sefc L, Babic M. Role of dextran in stabilization of polypyrrole nanoparticles for photoacoustic imaging. Eur. Polym. J. 2021,157:110634. https://doi.org/10.1016/j.eurpolymj.2021.110634

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• Kolokithas-Ntoukas A, Bakandritsos A, Belza J, Kesa P, Herynek V, Pankrac J, Angelopoulou A, Malina O, Avgoustakis K, Georgakilas V, Polakova K, Zboril R. Condensed Clustered Iron Oxides for Ultrahigh Photothermal Conversion and In Vivo Multimodal Imaging. ACS Appl. Mater. Interfaces. 2021; 13(25):29247-29256. https://doi.org/10.1021/acsami.1c00908

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• Keša P, Paúrová M, Babič M, Heizer T, Matouš P, Turnovcová K, Mareková D, Šefc L, Herynek V. Photoacoustic Properties of Polypyrrole Nanoparticles. Nanomaterials. 2021;11(9):2457. https://doi.org/10.3390/nano11092457

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• Loukotova L, Svec P, Groborz O, Heizer T, Benes H, Raabova H, Belinova T, Herynek V, Hruby M. Direct Comparison of Analogous Amphiphilic Gradient and Block Polyoxazolines. Macromolecules. 2021; 54(17):8182-8194. https://doi.org/1021/acs.macromol.0c02674

2020

• Wong WS, Alozy J, Ballabriga R, Campbell M, Kremastiotis I, Llopart X, Poikela T, Sriskaran V, Tlustos L, Turecek D. Introducing Timepix2, a frame-based pixel detector readout ASIC measuring energy deposition and arrival time. Radiat. Meas. 2020, 131(February), 106230. https://doi.org/10.1016/j.radmeas.2019.106230

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• Dreier ES, Silvestre C, Kehres J, Turecek D, Khalil M, Hemmingsen JH, Hansen O, Jakubek J, Feidenhans’l R, and Olsen UL. Single-shot, omni-directional x-ray scattering imaging with a laboratory source and single-photon localization. Opt Lett. 2020, 45(4), 1021-1024. https://doi.org/10.1364/OL.381420

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• Herynek V, Babič M, Kaman O, Charvátová H, Veselá M, Šefc L. Development of novel nanoparticles for MPI. Int J Mag Part Imag. 2020, 6(2):2009019. https://doi.org/10.18416/IJMPI.2020.2009019

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• Kozler P, Herynek V, Marešová D, Perez PD, Šefc L, Pokorný J. Effect of methylprednisolone on experimental brain edema in magnetic resonance imaging. Physiol Res. 2020; 69(5):919-926. https://doi.org/10.33549/physiolres.934460

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• Dezortova M, Lescinskij A, Dusek P, Herynek V, Acosta-Cabronero J, Bruha R, Jiru F, Robinson D, Hajek M. Multiparametric Quantitative Brain MRI in Neurological and Hepatic Forms of Wilson's Disease. J Magn Reson Imaging. 2020 Jun;51(6):1829-1835. https://doi.org/10.1002/jmri.26984

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• Kubíčková L, Kaman O, Veverka P, Herynek V, Brázda P, Vosmanská M, Kmječ T, Dvořák P, Kubániová D, Kohout J. The ɛ-AlxFe2-xO3 nanomagnets as MRI contrast agents: Factors influencing transverse relaxivity. Colloids Surf. A: Physicochem. Eng. 2020, 589(2); 204–214. https://doi.org/10.1016/j.colsurfa.2020.124423

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• Honěk J, Šrámek M, Honěk T, Tomek A, Šefc L, Januška J, Fiedler J, Horváth M, Novotný Š, Veselka J. Patent Foramen Ovale Closure Is Effective in Divers: Long-Term Results From the DIVE-PFO Registry. J Am Coll Cardiol. 2020;76(9):1149-1150. https://doi.org/10.1016/j.jacc.2020.06.072

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• Groborz O, Poláková L, Kolouchová K, Švec P, Loukotová L, Miriyala VM, Francová P, Kučka J, Krijt J, Páral P, Báječný M, Heizer T, Pohl R, Dunlop D, Czernek J, Šefc L, Beneš J, Štěpánek P, Hobza P, Hrubý M. Chelating Polymers for Hereditary Hemochromatosis Treatment. Macromol Biosci. 2020, 20(12):e2000254. https://doi.org/10.1002/mabi.202000254

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• Královec K, Havelek R, Koutová D, Veverka P, Kubíčková L, Brázda P, Kohout J, Herynek V, Vosmanská M, Kaman O. Magnetic nanoparticles of Ga-substituted ε-Fe2 O3 for biomedical applications: magnetic properties, transverse relaxivity and effects of silica-coated particles on cytoskeletal networks. J Biomed Mater Res A. 2020;108(7):1563-1578. https://doi.org/10.1002/jbm.a.36926

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• Kostiv, U, Kucka, J, Lobaz, V, Kotov, N, Janouskova, O, Slouf, M, Krajnik, B, Podhorodecki, A, Francova, P, Sefc, L, Jirak, D, Horak, D. Highly colloidally stable trimodal I-125-radiolabeled PEG-neridronate-coated upconversion/magnetic bioimaging nanoprobes. Sci Rep. 2020, 10(1): 20016. https://doi.org/10.1038/s41598-020-77112-z

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• Jager E, Sincari V, Albuquerque LJC, Jager A, Humajova J, Kucka J, Pankrac J, Paral P, Heizer T, Konefal R, Pavlova E, Sedlacek O, Giacomelli FC, Pouckova P, Sefc L, Stepanek P, Hruby M. Reactive oxygen species (ROS)-responsive polymersomes with site-specific chemotherapeutic delivery into ROS-rich tumors in vivo. Biomacromolecules. 2020;21(4):1437-1449. https://doi.org/10.1021/acs.biomac.9b01748

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• Walter A, Paul-Gilloteaux P, Plochberger B, Sefc L, Verkade P, Mannheim JG, Slezak P, Unterhuber A, Marchetti-Deschmann M, Ogris M, Bühler K, Fixler D, Geyer S, Weninger W, Glösmann M, Handschuh S, Wanek T. Correlated Multimodal Imaging in Life Sciences: Expanding the Biomedical Horizon. Front. Phys. 2020, 8:47. https://doi.org/10.3389/fphy.2020.00047

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• Pola R, Böhmová E, Filipová M, Pechar M, Pankrác J, Větvička D, Olejár T, Kabešová M, Poučková P, Šefc L, Zábrodský M, Janoušková O, Bouček J, Etrych T. Targeted Polymer-Based Probes for Fluorescence Guided Visualization and Potential Surgery of EGFR-Positive Head-and-Neck Tumors. Pharmaceutics. 2020, 12(1):31. https://doi.org/10.3390/pharmaceutics12010031

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• Turecek D, Jakubek J, Trojanova E, Sefc L. Single layer Compton camera based on Timepix3 technology. J Instrum. 2020;15(01):C01014-C. https://doi.org/10.1088/1748-0221/15/01/c01014

2019

• Pola R, Parnica J, Zuska K, Böhmová E, Filipová M, Pechar M, Pankrác J, Mucksová J, Kalina J, Trefil P, Šefc L, Větvička D, Poučková P, Bouček J, Janoušková O and Etrych T. Oligopeptide-targeted polymer nanoprobes for fluorescence-guided endoscopic surgery. Multifunct Mater. 2019;2(2). https://doi.org/10.1088/2399-7532/ab159e

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• Malina T, Poláková K, Skopalík J, Milotová V, Holá K, Havrdová M, Bartoň Tománková K, Čmiel V, Šefc L, Zbořil R. Carbon dots for in vivo fluorescence imaging of adipose tissue-derived mesenchymal stromal cells. Carbon. 2019,152: 434-443. https://doi.org/10.1016/j.carbon.2019.05.061

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• Hromádková V, Francová P, Báječný M, Jonas F, Molitor M, Šefc L, Měšťák O. The CD34+ Cell Number Alone Predicts Retention of the Human Fat-Graft Volume in a Nude Mouse Model. Folia Biol (Praha). 2019, 65(2):64-69. PMID: 31464182

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• Patsula V, Horak D, Kucka J, Mackova H, Lobaz V, Francova P, Herynek V, Heizer T, Páral P, Šefc L. Synthesis and modification of uniform PEG-neridronate-modified magnetic nanoparticles determines prolonged blood circulation and biodistribution in a mouse preclinical model. Sci Rep. 2019, 9:10765. https://doi.org/10.1038/s41598-019-47262-w

• Honěk J, Šrámek M, Šefc L, Januška J, Fiedler J, Horváth M, Tomek A, Novotný Š, Honěk T, Veselka J. High-grade patent foramen ovale is a risk factor of unprovoked decompression sickness in recreational divers. J Cardiol. 2019;74(6):519-523. https://doi.org/10.1016/j.jjcc.2019.04.014

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• Herynek V, Turnovcová K, Gálisová A, Kaman O, Mareková D, Koktan J, Vosmanská M, Kosinová L, Jendelová P. Manganese-Zinc Ferrites: Safe and Efficient Nanolabels for Cell Imaging and Tracking In Vivo. ChemistryOpen. 2019;8(2):155-165. https://doi.org/10.1002/open.201800261

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• Herynek V, Martinisková M, Bobrova Y, Gálisová A, Kotek J, Hermann P, Koucký F, Jirák D, Hájek M. Low-molecular-weight paramagnetic 19F contrast agents for fluorine magnetic resonance imaging. MAGMA. 2019;32(1):115-122. https://doi.org/10.1007/s10334-018-0721-9

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• Gálisová A, Herynek V, Swider E, Sticová E, Pátiková A, Kosinová L, Kříž J, Hájek M, Srinivas M, Jirák D. A Trimodal Imaging Platform for Tracking Viable Transplanted Pancreatic Islets In Vivo: F-19 MR, Fluorescence, and Bioluminescence Imaging. Mol Imaging Biol. 2019;21(3):454-464. https://doi.org/10.1007/s11307-018-1270-3

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• Kubickova L, Brazda P, Veverka M, Kaman O, Herynek V, Vosmanska M, Dvorak P, Bernasek K, Kohout J. Nanomagnets for ultra-high field MRI: Magnetic properties and transverse relaxivity of silica-coated epsilon-Fe2O3. J Magn Magn Mater. 2019, 480:154-163. https://doi.org/10.1016/j.jmmm.2019.02.067

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• Felix-Bautista, R., Gehrke, T., Ghesquiere-Dierickx, L., Reimold, M., Amato, C. - Tureček, D., Jakubek, J., Ellerbrock, M., Martisikova, M.. Experimental verification of a non-invasive method to monitor the lateral pencil beam position in an anthropomorphic phantom for carbon-ion radiotherapy. Phys Med Biol. 2019, 64(17):175019. https://doi.org/10.1088/1361-6560/ab2ca3

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• Dreier E.S., Silvestre C., Kehres J., Turecek D., Khalil M., Hemmingsen J.H., Hansen O., Jakubek J., Feidenhands I., Olsen U.L, Virtual subpixel approach for single-mask phase-contrast imaging using Timepix3. J Instrum. 2019,14:C01011. https://doi.org/10.1088/1748-0221/14/01/C01011

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• Khalil, M., Tureček, D., Jakubek, J., Kehres, J., Dreier, E. S., Olsen, U. L. Intrinsic XRF corrections in Timepix3 CdTe spectral detectors. J Instrum. 2019, 14, C01018. https://doi.org/10.1088/1748-0221/14/01/C01018